Meet the Partners - Universidad de Vigo
The Center for Nanosciences and Biomedical Research (CINBIO) at the University of Vigo in Northwest Spain is spearheading advancements in the biomedical and biotechnological fields, setting itself apart with its multidisciplinary approach. CINBIO is home to top-tier researchers from a diverse array of disciplines, including medicine, biology, chemistry, physics, mathematics, and computer science, all collaborating to push the boundaries of scientific knowledge and application.
Among the many specialized research groups at CINBIO, the Phylogenomics group stands out for its focus on the evolution of genomes, cells, populations, and species. This group integrates concepts and tools from biology, statistics, and computer science to explore complex evolutionary questions. Currently, two postdoctoral researchers, Nuria Estévez and João Alves, alongside Principal Investigator David Posada, are contributing their expertise to the groundbreaking 3DSecret project.
The 3DSecret project is dedicated to unravelling the complexities of cancer evolution through the innovative application of single-cell genomics. Leveraging their extensive experience in the genomics of tumour tissues and individual cancer cells, including circulating tumour cells (CTCs), the team is poised to make significant strides in understanding cancer at a granular level.
The research aims to analyze the genome and transcriptome of cell spheroids derived from single CTCs. Nuria Estévez will lead the DNA and RNA isolation and sequencing efforts, ensuring the accuracy and integrity of the genetic data. João Alves will handle the bioinformatic analysis, transforming raw sequencing data into meaningful insights. Overseeing the entire process, David Posada will ensure that each phase of the project is meticulously executed and aligned with the research objectives.
The multidisciplinary collaboration at CINBIO, exemplified by the 3DSecret project, underscores the University of Vigo’s commitment to fostering innovative research with the potential to transform our understanding and treatment of cancer.